Connecting Intellectual Disability with Cellular Transport: Whole exome sequencing reveals new mutations in molecular motor genes

By: David Shifrin, PhDLife Science Consultant and Freelance Writer In mice, mutations to genes encoding cellular transport proteins often lead to developmental problems, as well as defects in brain structure and function. For example, kinesins, a family of “molecular motors,” walk along networks of microtubule “tracks” made up of the protein tubulin. Together, these proteins… Read More Connecting Intellectual Disability with Cellular Transport: Whole exome sequencing reveals new mutations in molecular motor genes

What to do with incidental findings? A survey of the genetics community

By: David Shifrin Life Science Consultant and Freelance Writer With the implementation of exome sequencing (ES) and whole genome sequencing (WGS) for clinical use, the volume of data that can be obtained from any one individual is enormous. One of the significant issues facing genetics professionals, particularly from an ethical standpoint, is what to do… Read More What to do with incidental findings? A survey of the genetics community