Intellectual disability and cellular signaling: the role of Beta-catenin

By: David Shifrin, PhD Life Science Consultant and Freelance Writer Wnt signaling is arguably one of the most important signaling pathway in eukaryotes. Because it helps regulate stem cell decisions, it is involved in virtually every aspect of embryonic development and tissue renewal in adults. Defects in the pathway have been well characterized in various… Read More Intellectual disability and cellular signaling: the role of Beta-catenin

Electronic Health Records, Pt. 4: The Genetics Problem Cont…

By: David Shifrin, PhD Life Science Consultant and Freelance Writer This is the final part of the EHR series, and continues upon Part 3 where we began discussing the struggles EHR companies deal with as it relates to genetics. Accessing and Interpreting the Data Once the data is in the system, getting it back out… Read More Electronic Health Records, Pt. 4: The Genetics Problem Cont…

Electronic Health Records, Pt. 3: The Genetics Problem

By: David Shifrin, PhD Life Science Consultant and Freelance Writer The Underlying Problem Billions of base pairs, multiple software/computer systems, inconsistent language, a changing regulatory landscape, and the occasional sheet of paper, all combine to make the integration of genetic data into electronic health records (EHRs) an as-yet unsolved mess. Complex problems define current efforts… Read More Electronic Health Records, Pt. 3: The Genetics Problem

Electronic Health Records, Pt. 2: Theory vs. Reality of Implementation

By: David Shifrin, PhD Life Science Consultant and Freelance Writer In the previous post, we reviewed the history, purpose, and general perception of electronic health records (EHRs). Now, we dive deeper into how these systems are being implemented in clinical settings. Mixed Reviews: Professional Opinions and Use of EHRs A literature review and analysis of EHR implementation, carried… Read More Electronic Health Records, Pt. 2: Theory vs. Reality of Implementation

Electronic Health Records, Pt. 1: Where We’ve Come From

By: David Shifrin, PhD Life Science Consultant and Freelance Writer The Start of Something Big…and Messy The first obvious reference to an electronic health record (EHR) occured in 1958, in an article titled “Electronic Data Processing and Radiation Exposure Records.” The abstract reads, “A description is given of an application of electronic data processing methods… Read More Electronic Health Records, Pt. 1: Where We’ve Come From

New data access rights may be putting ethics and regulations at odds

By: David Shifrin, PhD Life Science Consultant and Freelance Writer While a “defective” and “daunting” event that resulted in “apparently unintended consequences” might make for a perfect movie plotline, it is far less ideal in real-world situations. Unfortunately, each of those terms was used in the abstract of a recent special article in Genetics in… Read More New data access rights may be putting ethics and regulations at odds