Mapping the genetics of treatment-resistant prostate cancer

By: David Shifrin, PhD Science Writer, Filament Life Science Communications What happens when a disease becomes resistant to all known therapies? The two instances that first come to mind are multi-resistant bacterial infections, and any number of cancers. In the latter category, metastatic prostate cancer frequently becomes resistant to available therapeutics. Androgen deprivation therapy is a… Read More Mapping the genetics of treatment-resistant prostate cancer

New Genetic Mutations Identified in Autism Spectrum Disorders

By: David Shifrin, PhD Science Writer, Filament Life Science Communications A couple of months ago, this blog published a post on two recent papers dealing with new advances in research on the genetics of autism spectrum disorders (ASD). In one, the authors were able to identify autism with high accuracy using gene expression levels. In the… Read More New Genetic Mutations Identified in Autism Spectrum Disorders

Panel Testing, Part 3: Recommended Use for Panel Tests

By: David Shifrin, PhD Science Writer, Filament Life Science Communications Last September, The National Comprehensive Cancer Network published an update to their guidelines for Genetic/Familial High-Risk Assessment for Breast and Ovarian cancers. This extensive document included a large section discussing the use of multi-gene panel testing. Again highlighting the uncertainty and concern, the first paragraph of… Read More Panel Testing, Part 3: Recommended Use for Panel Tests